Santa Clara University



Course Descriptions

Lower-Division Undergraduate Bioengineering Core Courses

BIOE 10 Introduction to Bioengineering
An introduction to the central topics of bioengineering, including the application of engineering methods and science to problems in biology and medicine, and the integration of engineering and biology. Current issues and opportunities in the field will be discussed. Course may include lectures, class discussions, guest lectures, field trips, short lab exercises, and team projects. (4 units)

BIOE 21 Introduction to Physiology
This course will cover five anatomical systems and how the structure of the human body relates to and defines its function in maintaining homeostasis. This course will introduce cytology, histology and also focus on diseases related to the skeletal, nervous, sensory, muscular, endocrine and reproductive systems. (4 units)

BIOE 22 Introduction to Cell and Molecular Bioengineering
The aim of this course is to introduce students to fundamental concepts in cell and molecular biology. Topics covered in the course will include cellular structure and function, biological molecules, molecular mechanism of cellular function, cell proliferation and signaling. This course will also emphasize the importance of applications of genetic engineering in human health and diseases. Course will include lectures, peer reviewed papers, class discussion, short lab exercises, and team projects. (4 units)

BIOE 22L Laboratory for BIOE 22
Co-requisite: BIOE 22. (1 unit)

BIOE 153 Biomaterials Science
An introduction into materials used for medical devices. Focus areas include: materials science, biology, biochemistry, practical aspects of biomaterials, industry literature and applications. Prerequisite: CHEM 13. (4 units)

Upper-Division Undergraduate Bioengineering Core Courses

BIOE 154 Introduction to Biomechanics
Overview of basic human anatomy, physiology, and anthropometry. Analysis of human motion and function, and injury. Review of issues related to designing devices for use in, or around, the human body including safety, biocompatibility, ethics, and FDA regulations. Also listed as MECH 254. Prerequisites: BIOE 10, PHYS 33. (4 units)

BIOE 155 Biological Transport Phenomena
The transport of mass, momentum, and energy are critical to the function of living systems and the design of medical devices. This course develops and applies scaling laws and the methods of continuum mechanics to biological transport phenomena over a range of length and time scales. Prerequisites: AMTH 106, BIOE 10, PHYS 33. (4 units)

BIOE 161 Bioinstrumentation
Transducers and biosensors from traditional to nanotechnology; bioelectronics and measurement system design; interface between biological system and instrumentation; data analysis; clinical safety. Laboratory component will include traditional clinical measurements and design and test of a measurement system with appropriate transducers. Also listed as ELEN 161. Prerequisites: BIOE 21 (or BIOL 21), ELEN 50. (4 units)

BIOE 161 L Laboratory for BIOE 161
Co-requisite: BIOE 161 (1 unit)

BIOE 162 BioSignals and Processing
Origin and characteristics of bioelectric, bio-optical, and bioacoustic signals generated from biological systems. Behavior and response of biological systems to stimulation. Acquisition and interpretation of signals. Signal processing methods include FFT spectral analysis and time-frequency analysis. Laboratory component will include modeling of signal generation and analysis of signals such as electrocardiogram (ECG), electromyogram (EMG), and vocal sound pressure waveforms. Also listed as ELEN 162. Prerequisites: AMTH 106, BIOE 10, ELEN 50. (4 units)

BIOE 162 L Laboratory for BIOE 162
Co-requisite: BIOE 162 (1 unit)

BIOE 163 Bio-Device Engineering
This course will instruct students with the fundamental principles of bio-device design, fabrication and biocompatibility, and let students experiment with the state-of-the-art bio-devices. Students will gain the hands-on experience with these bio-instruments which are also used in the field. Emphasis is given to the cutting-edge applications in biomedical diagnostics and pharmaceutical drug discovery and development, particularly detection and monitoring interaction, and activity of biomolecules, such as enzymes, receptors, antibody, nucleic acids, and bioanalytes. Prerequisites: BIOL 25 or BIOE 22 & CHEM 31 (4 units)

BIOE 163 L Laboratory for BIOE 163
Co-requisite: BIOE 163. (1 unit)

BIOE 167 Medical Imaging Systems
Overview of medical imaging systems including sensors and electrical interfaces for date acquisition, mathematical models of the relationship of structural and physiological information to senor measurements, resolution and accuracy limits based on the acquisition system parameters, impact of the imaging system on the volume being imaged, data measured, and conversion process from electronic signals to image synthesis. Analysis of the specification and interaction of the functional units of imaging systems and the expected performance. Focus on MRI, CT, ultrasound, PET, and impedance imaging. Also listed as ELEN167. Prerequisites: BIOE 162/ELEN 162 or ELEN 110 or MECH 142. (4 units)

BIOE 171 Physiology & Anatomy for Engineers
This course examines the structure and function of the human body and the mechanisms for maintaining homeostasis. The course will provide a molecular-level understanding of human anatomy and physiology in select organ systems. The course will include lectures, class discussions, case studies, computer simulations, field trips, lab exercises and team projects. Prerequisite: BIOL 21 (or BIOL 21). (4 units)

BIOE 171 L Laboratory for BIOE 171
Co-requisite: BIOE 171 (1 unit)

BIOE 172 Tissue Engineering I
This course will introduce the basic principles underlying the design and engineering of functional biological substitutes to restore tissue function. Cell sourcing, manipulation of cell fate, biomaterial properties and cell-material interactions, and specific biochemical and biophysical cues presented by the extracellular matrix will be discussed, as well as the current status and future possibilities in the development of biological substitutes for various tissue types. Prerequisite: BIOE 22 or BIOL 254. (4 units)

BIOE 172 L Laboratory for BIOE 172
Co-requisite: BIOE 172. (1 unit)

BIOE 173 Tissue Engineering II
This course will provide a detailed overview of the progress achieved in developing tissue engineering therapies for a wide variety of human diseases and disorders. It will organized into two sections; the first section will provide a basic overview of in vivo tissue growth and development, tools and materials needed to design tissues and organs, stem cell biology and other emerging technologies. This basic section will be complemented by a series of recent examples in applying tissue engineering to various organ systems. Prerequisite: BIOE 172. (4 units)

BIOE 174 Microfabrication and Microfluidics for Bioengineering Applications
Focuses on those aspects of micro/nanofabrication that are best suited to BioMEMS and microfluidics to better understand and manipulate biological molecules and cells. The course aims to introduce students to the state-of-art applications in biological and biomedical research through lectures and discussion of current literature. A team design project that stresses interdisciplinary communication and problem solving is one of the course requirements. Also listed as ENGR 254. Prerequisite: BIOE 10, BIOE 21 (or BIOL 21) (4 units)

BIOE 175 Biomolecular and Cellular Engineering I
This course will focus on solving problems encountered in the design and manufacturing of biopharmaceutical products, including antibiotics, antibodies, protein drugs and molecular biosensors, with particular emphasis on the principle and application of protein engineering and reprogramming cellular metabolic networks. Prerequisites: BIOL 25 or BIOE 22& CHEM 31, or equivalent knowledge and by instructor's permission. BIOE 153 is recommended. (4-units)

BIOE 175L Laboratory for BIOE 175
Co-requisite: BIOE 175. (1 unit)

BIOE 176 Biomolecular and Cellular Engineering IIThis course will focus on the principle of designing, manufacturing synthetic materials and their biomedical and pharmaceutical applications. Emphasis of this class will be given to chemically synthetic materials, such as polymers, inorganic and organic compounds. Prerequisites: BIOE 175. BIOE 171 is recommended. (4-units)

BIOE 194 Design Project I
Specification of an engineering project, selected with the mutual agreement of the student and the project advisor. Complete initial design with sufficient detail to estimate the effectiveness of the project. Initial draft of the project report. (2 units)

BIOE 195 Design Project II
Continued design and construction of the project, system, or device. Second draft of project report. Prerequisites: BIOE 194. (2 units)

BIOE 196 Design Project III
Continued design and construction of the project, system, or device. Final report. Prerequisites: BIOE 195. (2 units)

Bioengineering Electives

BIOE 100 Bioengineering Research Seminar
A series of one-hour seminars will be presented by guest professors and researchers on their particular research topics in bioengineering or related fields. Students are required to attend 4~5 seminars and submit a one-page report summarizing the presentation for each seminar. May be repeated for credits. (1 unit) (Grading: P/NP)

BIOE 107 Medical Device Product Development
The purpose of this course is to provide background information and knowledge to start or enhance a career in medical device product development. Discusses medical device examples, product development processes, regulation, industry information, and intellectual property. Cross-listed with EGMT 307. (2 units)

BIOE 156 Introduction to Biomaterials
Introduction to each class of biomaterial. Exploration of research, commercial, and regulatory literature. Written and oral reports by students on a selected application requiring one or more biomaterials. Also listed as MECH 256. (2 units)

BIOE 157 Introduction to Biofuel Engineering
Introduction to biofuel science and production for engineers. Basic cell physiology and biochemical energetics will be rviewed. Fundamentals of bioreactor technology will be introduces as a foundation for biofuel manufacturing. This will include cell growth models, biochemical and photobioreactor systems, and other processes related to the production of biofuels such as ethanol, methane and biodiesel. Promising technologies such as algae based systems, genetically engineered enzymes and microbes, and microbial fuel cells will be discussed. An overview of the economics of production, including feestock, manufacturing and capital and operating costs, as well as current biofuel prices, will be given. Also listed as ENGR 257. (2 units)

BIOE 198 Internship
Directed internship in local bioengineering and biotech companies or research in off-campus programs under the guidance of research scientists or faculty advisors. Required to submit a professional research report. Open to upper-division students. (Variable units)

BIOE 199 Supervised Independent Reserach
By arrangement. Faculty advisor required. (1–4 units)