Santa Clara University

Department of Chemistry & Biochemistry

Michael R. Carrasco

Professor and Chair
Department of Chemistry & Biochemistry

(408) 551-1878
(408) 554-7811 fax
Alumni Science 162


Degree Information:

B.A., University of California, Berkeley, 1990
M.A., Columbia University, 1991
M.Phil., Columbia University, 1994
Ph.D., Columbia University, 1995


Organic Chemistry I, II, III (Chem 31, Chem 32, Chem 33)
Bioorganic Chemistry (Chem 194)


Site-specific attachment of small organic molecules to peptides and proteins, and how the structure and function of the peptides and proteins are altered by the attached molecules.

Active Grants:

“Henry Dreyfus Teacher-Scholar Award", Camille and Henry Dreyfus Foundation, 2004-2009, $60,000

Recent Publications:

Undergraduate coauthors are underlined.

M. R. Carrasco, O. Silva, K. A. Rawls, M. S. Sweeney, and A. A. Lombardo, "Chemoselective alkylation of N-alkylaminooxy-containing peptides", Org. Lett., 8, 3529-3532 (2006).

M. R. Carrasco, R. T. Brown, V. H. Doan, S. M. Kandel, and F. C. Lee, "2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid, an amino acid for the synthesis of mimics of O-linked glycopeptides", Biopolymers (Peptide Science), 84, 414-420 (2006).

Recent Presentations:

M. R. Carrasco, O. Silva, K. A. Rawls, M. S. Sweeney, and A. A. Lombardo, "'Post-translational' modification of synthetic peptides by chemoselective alkylation of N-alkylaminooxy amino acids", 9th Chinese International Peptide Symposium, Shanghai, China, July 3-6, 2006.

M. R. Carrasco, K. A. Rawls, M. S. Sweeney, O. Silva, and A. A. Lombardo, "Synthesis of neolipopeptides by chemoselective alkylation of N-alkylaminooxy-containing peptides", Peptides Gordon Conference, Ventura, CA, February 19-24, 2006.

M. R. Carrasco, "N-Alkylaminooxy amino acids as versatile derivatives for "post-translational" modifications of synthetic peptides", 19th American Peptide Symposium, San Diego, CA, June 18-23, 2005.


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